BALTIMORE - The skidding Baltimore Orioles lost to the San Francisco Giants, 5-3, Wednesday night at Camden Yards. Mike Yastrzemski homered on the game's first pitch, Michael Conforto also hit a solo shot for the Giants, who took the first two games in the series.

Analyzing Thursday’s San Francisco Giants at Baltimore Orioles odds and lines, with MLB expert picks, predictions and best bets.

Anthony Santander hit a game-ending, two-run home run with two outs in the bottom of the ninth inning to propel the Baltimore Orioles past the San Francisco Giants 5-3 on Thursday afternoon.