In terms of the chassis, the Multistrada V4 and V4 S have a lightweight aluminium monocoque frame, with a double-sided swingarm in shell-cast aluminium that has been repositioned one millimetre higher than before. This means an increased anti-squat effect of the suspension to make riding more precise and effective even at full load.

Visually, the Multistrada V4 RS distinguishes itself using a dedicated colour pattern. The Iceberg White colour, as it is called, along with the contrasting red stripes gives the bike a sporty appearance. There are red accents on the brake calipers and the spokes on the wheels. Adding to the looks is the single-sided swingarm.

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Ducati kicked off its World Première 2025 festivities with a bang, in the form of updates to three members of the Multistrada V4 family. The 2025 Multistrada V4, V4 S, and V4 Pikes Peak all get several key rider (and passenger) focused upgrades,

The Pikes Peak model of the 2025 Multistrada V4 range comes standard with an Akrapovic titanium silencer. This model is available in three color options: red, white, and black. However, the latter two colors are exclusive to the higher-spec S variant.

Ducati Multistrada V4 Pike Peak has broken cover in international markets. For the uninitiated, the Pikes Peak is the road-biased, sportier version of the Multistrada V4. For 2025, the bike has received visual tweaks along with new components.