Chiefs vs. Bills may be the game of the week. Mahomes and Josh Allen have faced off a total of seven times, with Mahomes winning four of those matchups. However, it's Allen who ha

Steelers-Ravens and Chargers-Bengals will also significantly impact the AFC playoff picture. Our writers and editors pick winners in all 14 games.

At the time of posting, the Bills are the home-team favorite to beat the Chiefs in Week 11. That team in any game usually gets a three-point edge in the spread, and the line is at -2.5 in favor of Buffalo… so it’s practically a pick ’em.